陶庆华
陶庆华 博士
教授，博导
1992 四川大学生物工程系遗传学专业 学士
2000 中科院上海细胞所发育生物学专业 博士
2000—2008 美国俄亥俄州辛辛那提市儿童医院发育生物学系 博士后
2008—至今 清华大学生命科学学院 教授
综合运用现代分子生物学，系统生物学和实验胚胎学手段，以非洲爪蟾（Xenopus）和胚胎干细胞为主要模式生物，探索脊椎动物早期胚胎发育中的基本生物学现象及生殖相关疾病发生的分子机理。主要研究兴趣和方向包括：
1．WNT信号通路在胚胎早期发育和胚胎干细胞分化中的功能及其调控
2．细胞粘连分子 (cadherins) 在胚胎形态建成及细胞迁移中的功能
3．胚胎多潜能前体细胞分化中的表观遗传控制机理
4. 卵母细胞成熟的控制机理和母性基因在脊椎动物早期胚胎发育中的功能研究
·Tao QH, Nandadasa S, McCrea P, Heasman J and Wylie C. (2007) G
protein-coupled signals control actin assembly by controlling cadherin
expression in the early Xenopus embryos. Development, 134(14):2651-61.
·Tao QH, Yokota C, Puck H, Kofron M, Birsoy B, Dong Y, Asashima M, Wylie
C, Lin X and Heasman J. (2005a). Maternal Wnt11 activates the canonical
Wnt signaling pathway required for axis formation in Xenopus embryos.
Cell 120:857-871.
·Tao QH, Lloyd B, Lang S, Houston D, Zorn A, and Wylie C. (2005b). A
novel G protein coupled receptor, related to GPR4, is required for
assembly of the cortical actin in early Xenopus embryos. Development.
132:2825-2836.
·Lloyd B, Tao QH, Lang S and Wylie C (2005). Lysophosphatidic acid
signaling controls actin assembly and cytoarchiteture in Xenopus
embryos. Development. 132:805-816.
·Liao GH, Tao QH, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsien JC,
Wylie C, Heasman J and Kuan CY. (2006) JNK prevents nuclear b catenin
accumulation and regulates axis formation in Xenopus embryos. P.N.A.S.,
103(44): 16313-8.
·Kofron M., Birsoy B., Houston D., Tao QH, Wylie C. and Heasman J.
(2007). Wnt11/beta-catenin signaling in both oocytes and early embryos
acts thorugh LRP6-mediated regulation of axin. Developoment, 134(3):
503-13.
·Cha SW, Tadjuidje E, Tao QH, Wylie C, Heasman J(2008). Wnt5a and Wnt11
interact in a maternal Dkk1-regulated fashion to activate both canonical
and non-canonical signaling in Xenopus axis formation. Development.
2008 Nov;135(22):3719-29.
·Sundaram N, Tao QH, Wylie C and Heasman J. (2003). The role of maternal
CREB in early embryogenesis of Xenopus laevis. Dev Biol. 261(2):337-52.
·Xanthos JB, Kofron M, Tao QH, Schaible K, Wylie C, Heasman J. (2002).
The roles of three signaling pathways in the formation and function of
the Spemann Organizer. Development. 129(17):4027-43.
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