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段明星

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主要科研领域与方向

生物化学与分子生物学

多肽蛋白质药物的性质及功能;多肽蛋白质药物的口服及缓释;核酸疫苗的构建及免疫机理和免疫途径;生物大分子的透皮吸收

成果

现已发表文章 90篇,申请专利20项(授权1项美国专利,授权13项中国专利)。

参加学术团体

中国生物化学与分子生物学会海洋分会理事(2008年)

中国药学会高级会员;中国生物化学与分子生物学会会员

中国药学杂志编委(2006年);现代科学仪器杂志编委(2006年)

代表性出版物

  • F.F.Zhuang, R.Liang, C.T.Zou, H.Ma, C.X.Zheng, M.X.Duan*.“High efficient encapsulation of plasmid DNA in PLGA microparticles by organic phase self-emulsification”, J.Biochem.Biophys.Methods 52 (2002) 169-178.
  • Bin Deng, Zheng Liu, Guoan Luo*, Hong Ma, Mingxing Duan*.“Rapid quantitative determination and assessment of insulin in oil formulation by micellar electrokinetic capillary chromatography”, Journal of Pharmaceutical and Biomedical Analysis. 27 73 - 80 (2002).
  • Liang Rong,Zhuang FengFeng, Meng Zheng, Zheng Changxue, Duan Mingxing*.“A New Potent Route of DNA Vaccine Inoculation: DNA-Liposome Complexes on Bare Skin Induce Antigen-Special Antibody Responses”, Molecules 8, 120 126. (2003).
  • Hong-Wei Wang, Yong Chen, Hsiuchin Yang, Xianchuan Chen, Ming-Xing Duan, Phang C. Tai* and Sen-Fang Sui*.“Ring Like Pore Structures of SecA: Implication for Bacterial Protein-Conducting Channels”. Proc.Natl.Acad.Sci.U.S.A. Vol.100 No.7 P4221-4226 (2003).
  • Xi-Ming Qin,Ming-Xing Duan*, Bin Deng, Xi-Cheng Liu, Qiang-Zhe Zhang, Zheng Liu, and Hong-Xuan He.“Isolation and Identification of a New Thymic Peptide from Calf Thymus”, Biochemistry(Moscow) 2004, 69(8): 921-925.
  • HongXuan HE, BaoHua ZHAO, LiYan LIU,Kai ZHOU, XiMing QIN, QiangZhe ZHANG, Xi LI, ChangXue ZHENG, and MingXing DUAN*.“The Humoral and Cellular Immune Responses in Mice Induced by DNA Vaccine Expressing the Sporozoite Surface Protein of Cryptosporidium parvum”, DNA AND CELL BIOLOGY Vol.23, No.5, P335-339 (2004).
  • Zhang Qiang-Zhe, Qin Xi-Ming,Dong Hai-Li, Liang Rong, He Hong-Xuan,Li Xi, Jiang Bei-Yu, Liu Xiang-Jun, Duan Ming-Xing*.“Efficient Protection of H5N1 Influenza Virus DNA Vaccine Delivering by Electroporation in Mammalian and Avian System”, Progress in Biochemistry and Biophysics Vol.32 No.8 p726-733 (2005).
  • Hongxuan HE, Yi Tang, Ximing Qin, Wenbo XU, Yifei Wang , Xiangjun Liu, Xingyou Liu, Sheng Xiong, Jiuxiang Li, Meiying Zhang, Mingxing DUAN*.“Construction of a eukaryotic expression plasmid encoding partial S gene fragments of the SARS- CoV and its potential utility as a DNA vaccine”. DNA and Cell Biology Aug 2005 Vol.24, No.8 516-520.
  • Er-li MA, Hong MA, Zheng LIU, Chang-xue ZHENG, Ming-xing DUAN*“ In vitro and in vivo evaluation of a novel oral insulin formulation” Acta Pharmacologica Sinica 2006 Oct,27(10):1382-1388
  • GONG Qiu, LIU Zheng, ZHAO, Weigang, MA Hong, ZHANG Jing, MA Er-li, ZHENG, Chang-xue, DUAN Ming-xing*“Studies on Administration and Mechanism of Insulin Oily Formulation”Chinese Pharmaceutical Journal 2007 Sep, Vol.42 No.17 P1320-1324
  • Kai Zhou, Hongxuan He ∗, YanyunWu, Mingxing Duan ∗“RNA interference of avian influenza virus H5N1 by inhibiting viral mRNA with siRNA expression plasmids” Journal of Biotechnology 135(2008)140-144
  • Wang Guan, Xu Min, Zhou Huafeng, Chen Bin, Yan Zemin, Duan Ming-xing. ∗“Stady on Bile Acids From Bile Juice of Snake,Chicken and Pig by Reversed Phase High Performance Liquid Chromatography and their Antibacterial Effects”Modern Scientific Instruments, No.3 P50-55, Jun 2008.
  • Chengmin Wang, Hongxuan He ∗, Mingxing Duan“Development and evaluation of a recombinant CP23 antigen-based ELISA for serodiagnosis of Cryptosporidium parvum ” Experimental Parasitology 121(2009)157-162
  • Jieli Deng,Zhonghan Sheng,Kai Zhou, Mingxing Duan ∗, Chu-yi Yu ∗, and Long Jiang ∗“Construction of Effective Receptor for Recognition of Avion Influenza H5N1 Protein HA1 by Assembly of Monohead Glycolipids on Polydiacetylene” Bioconjugate Chemistry Vo.20 No.3 P533-537 (2009)
  • Huafeng Zhou,Yang Yue,Guanlan Liu, Yan Li, Jing Zhang, Qiu Gong,Zemin yan,Mingxing Duan∗“Preparation and Characterization of a Lecithin Nanoemulsion as a Topical Delivery System” Nanoscale Research Letter (2010) 5:224–230.
  • Yang Yue, Huafeng Zhou, Guanlan Liu, Yan Li, Zemin Yan, Mingxing Duan∗“The advantages of a novel CoQ10 delivery system in skin photo-protection”International Journal of Pharmaceutics 392(2010)57-63

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