分节
分节的类型与生物学意义编辑本段
分节可分为体节分节(Somitic Segmentation)和体节模式(Metamerism)两大类:
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分节的意义在于提高运动效率、增强环境适应能力,并为复杂器官系统的进化提供模块化基础。
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脊椎动物的分节机制编辑本段
无脊椎动物的分节机制编辑本段
分节的分子调控编辑本段
分节异常与疾病编辑本段
研究意义编辑本段
参考资料编辑本段
- Dequéant, M. L., & Pourquié, O. (2008). Segmental patterning of the vertebrate embryonic axis. Nature Reviews Genetics, 9(5), 370-382.
- Kageyama, R., Ohtsuka, T., & Kobayashi, T. (2007). The Hes gene family: repressors and oscillators that orchestrate embryogenesis. Development, 134(7), 1243-1251.
- Perrimon, N., Pitsouli, C., & Shilo, B. Z. (2012). Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harbor Perspectives in Biology, 4(8), a005975.
- Wolpert, L., Tickle, C., & Arias, A. M. (2015). Principles of Development (5th ed.). Oxford University Press.
- Gilbert, S. F. (2016). Developmental Biology (11th ed.). Sinauer Associates.
- Lewis, J. (2003). Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator. Current Biology, 13(16), 1398-1408.
- Hubaud, A., & Pourquié, O. (2014). Signalling dynamics in vertebrate segmentation. Nature Reviews Molecular Cell Biology, 15(5), 309-321.
- Tian, Y., & Manley, N. R. (2020). The segmentation clock: mechanisms of periodic gene expression in the vertebrate embryo. Development, 147(18), dev189860.
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