陶庆华

陶庆华，博士，清华大学教授，博士生导师。 ADSFAEQWER353423413434

• 1992年：四川大学生物工程系遗传学专业 学士
• 2000年：中国科学院上海细胞所发育生物学专业 博士

• 2000－2008年：美国俄亥俄州辛辛那提市儿童医院发育生物学系 博士后
• 2008年至今：清华大学生命科学学院 教授

综合运用现代分子生物学、系统生物学和实验胚胎学手段，以非洲爪蟾（Xenopus）和胚胎干细胞为主要模式生物，探索脊椎动物早期胚胎发育中的基本生物学现象及生殖相关疾病发生的分子机理。主要研究兴趣和方向包括： ADFASDFAF23RQ23R

1. WNT信号通路在胚胎早期发育和胚胎干细胞分化中的功能及其调控
2. 细胞粘连分子（cadherins）在胚胎形态建成及细胞迁移中的功能
3. 胚胎多潜能前体细胞分化中的表观遗传控制机理
4. 卵母细胞成熟的控制机理和母性基因在脊椎动物早期胚胎发育中的功能研究

• Tao QH, Nandadasa S, McCrea P, Heasman J and Wylie C. (2007) G protein-coupled signals control actin assembly by controlling cadherin expression in the early Xenopus embryos. Development, 134(14):2651-61.
• Tao QH, Yokota C, Puck H, Kofron M, Birsoy B, Dong Y, Asashima M, Wylie C, Lin X and Heasman J. (2005a). Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos. Cell 120:857-871.
• Tao QH, Lloyd B, Lang S, Houston D, Zorn A, and Wylie C. (2005b). A novel G protein coupled receptor, related to GPR4, is required for assembly of the cortical actin in early Xenopus embryos. Development. 132:2825-2836.
• Lloyd B, Tao QH, Lang S and Wylie C (2005). Lysophosphatidic acid signaling controls actin assembly and cytoarchiteture in Xenopus embryos. Development. 132:805-816.
• Liao GH, Tao QH, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsien JC, Wylie C, Heasman J and Kuan CY. (2006) JNK prevents nuclear b catenin accumulation and regulates axis formation in Xenopus embryos. P.N.A.S., 103(44): 16313-8.
• Kofron M., Birsoy B., Houston D., Tao QH, Wylie C. and Heasman J. (2007). Wnt11/beta-catenin signaling in both oocytes and early embryos acts thorugh LRP6-mediated regulation of axin. Developoment, 134(3): 503-13.
• Cha SW, Tadjuidje E, Tao QH, Wylie C, Heasman J (2008). Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development. 2008 Nov;135(22):3719-29.
• Sundaram N, Tao QH, Wylie C and Heasman J. (2003). The role of maternal CREB in early embryogenesis of Xenopus laevis. Dev Biol. 261(2):337-52.
• Xanthos JB, Kofron M, Tao QH, Schaible K, Wylie C, Heasman J. (2002). The roles of three signaling pathways in the formation and function of the Spemann Organizer. Development. 129(17):4027-43.

电话：62795413

ADFASDFAF23RQ23R

ADFASDFAF23RQ23R

• Tao QH, Nandadasa S, McCrea P, et al. G protein-coupled signals control actin assembly by controlling cadherin expression in the early Xenopus embryos. Development, 2007, 134(14): 2651-2661.
• Tao QH, Yokota C, Puck H, et al. Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos. Cell, 2005, 120(6): 857-871.
• Tao QH, Lloyd B, Lang S, et al. A novel G protein coupled receptor, related to GPR4, is required for assembly of the cortical actin in early Xenopus embryos. Development, 2005, 132(12): 2825-2836.
• Lloyd B, Tao QH, Lang S, et al. Lysophosphatidic acid signaling controls actin assembly and cytoarchitecture in Xenopus embryos. Development, 2005, 132(4): 805-816.
• Liao GH, Tao QH, Kofron M, et al. JNK prevents nuclear β-catenin accumulation and regulates axis formation in Xenopus embryos. PNAS, 2006, 103(44): 16313-16318.
• Kofron M, Birsoy B, Houston D, et al. Wnt11/β-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin. Development, 2007, 134(3): 503-513.
• Cha SW, Tadjuidje E, Tao QH, et al. Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development, 2008, 135(22): 3719-3729.
• Sundaram N, Tao QH, Wylie C, et al. The role of maternal CREB in early embryogenesis of Xenopus laevis. Dev Biol, 2003, 261(2): 337-352.
• Xanthos JB, Kofron M, Tao QH, et al. The roles of three signaling pathways in the formation and function of the Spemann Organizer. Development, 2002, 129(17): 4027-4043.
• Heasman J. Maternal determinants of embryonic cell fate. Semin Cell Dev Biol, 2006, 17(1): 93-98.
• Wylie C, Kofron M, Heasman J. The maternal role of Wnt signaling in Xenopus axis formation. Int J Dev Biol, 2006, 50(2-3): 217-224.
• 陶庆华, 贺熹. Wnt 信号通路与胚胎发育. 遗传, 2008, 30(9): 1103-1108.
• 张旭, 陶庆华. 非洲爪蟾早期胚胎发育中细胞粘连分子的功能研究进展. 中国细胞生物学学报, 2010, 32(6): 835-842.