Daqing Li

Daqing Li, M.D.

Professor of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania

Attending and Clinical Director of the Resident Clinic , Dept. of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Health System

Director of Gene and Molecular Therapy laboratory, Dept. of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Health System

Director of International Visiting Physician Program, Dept. of Otorhinolaryngology-Head & Neck Surgery, University of Pennsylvania School of Medicine

Director of the Temporal Bone Lab, Dept. of Otorhinolaryngology: Head & Neck Surgery, University of Pennsylvania Health System

Description of Research Expertise

Basic and Translational Research in Otorhinolaryngology-Head & Neck Surgery:
Vector Development and Targeted Gene Delivery in Ear, Nose,Throat, Head & Neck
Molecular Approach for the Treatment of Head & Neck Cancer
Molecular Approach for the Treatment of Inner Ear Disease

Description of Clinical Expertise

Otology and Neurotology

Selected Publications

Waleed M. Abuzeid, Xiaoling Jiang, Guoli Shi, Hui Wang, David Paulson, Koji Araki, David Jungreis, James Carney, Bert W. O’Malley, Jr. and Daqing Li. : Molecular Disruption of Rad50 Sensitizes Tumor Cells to Cisplatin-based Chemotherapy. Journal of Clinical Investigation 119: 1974-1985, 2009.

Mindy R. Figures, Jessie Wobb, Koji Araki, Tingyan Liu, Lei Xu, Hanjing Zhu, Bert W. O’Malley Jr, and Daqing Li: Head and Neck Squamous Cell Carcinoma Targeted Chemosensitization. Otolaryngology-Head and Neck Surgery 141: 177-183, 2009.

Khurram Khan, Koji Akraki, Daiyou Wang, Guayan Li, Xin Li, Jie Zhang, Weizheng Xu, Randall K. Hoover, Susan Lauter, Bert O'Malley, Jr., Rena G. Lapidus, Daqing Li.: Head and neck cancer radiosensitization by the novel poly(ADP-ribose) polymerase inhibitor GPI-15427. Head and Neck 32: 381-391, 2010.

Paulson, David P. Abuzeid, Waleed. Jiang, Hao. Oe, Tomoyuki. O'Malley, Bert W. Li, Daqing.:A novel controlled local drug delivery system for inner ear disease. Laryngoscope 118(4): 706-11, Apr 2008.

Koji Araki, Sidrah Ahmad, Guoyan Li, David Bray,Jr., Koichiro Saito, Daiyou Wang, Uwe Wirtz, Sunil Sreedharan, Bert O'Malley Jr., Daqing Li : Retinoblastoma RB94 enhances radiation treatment of head and neck squamous cell carcinoma. Clinical Cancer Research 14 (11): 3514-3519, June 2008.

Daqing Li, Charles M. Henley and Bert W. O’Malley: Distortion Product Otoacoustic Emissions and Outer Hair Cell Defects in the hyt/hyt Mutant Mouse. Hearing Research(138), 65-72, 1999

Chris S. Moe, Daqing Li, Thomas Linder, Stephan Schmid and Ugo Fisch: An Update on the Surgical Treatment of Temporal Bone Paraganglioma. Skull Base Surgery(9), 185-194, 1999.

Daqing Li (co-first author), Mengqing Xiang, Lin Gan, Lijuan Zhou, Bert W. O’Malley, Jr., William Klein and Jeremy Nathans: Essential Role of POU-Domain Factor Brn-3c in Auditory and Vestibular Hair Cell Development. Proceedings of the National Academy of Sciences(94), 9445-9450, 1997.

Daqing Li, Barbara Schauble, Carl Moll and Ugo Fisch: Intratemporal Facial Nerve Perineurioma. Laryngoscope(106), 328-333, 1996.

Daqing Li and Yulin Cao: Facial Nerve Dehiscence: A Report of 1465 Stapes Surgeries. Annals of Otology, Rhinology & Laryngology(105), 467-471, 1996.