段明星

主要科研领域与方向

生物化学与分子生物学

多肽蛋白质药物的性质及功能；多肽蛋白质药物的口服及缓释；核酸疫苗的构建及免疫机理和免疫途径；生物大分子的透皮吸收

成果

现已发表文章 90篇，申请专利20项（授权1项美国专利，授权13项中国专利）。

参加学术团体

中国生物化学与分子生物学会海洋分会理事(2008年)

中国药学会高级会员；中国生物化学与分子生物学会会员

中国药学杂志编委（2006年）；现代科学仪器杂志编委（2006年）

代表性出版物

• F.F.Zhuang, R.Liang, C.T.Zou, H.Ma, C.X.Zheng, M.X.Duan.“High efficient encapsulation of plasmid DNA in PLGA microparticles by organic phase self-emulsification”, J.Biochem.Biophys.Methods 52 (2002) 169-178.
• Bin Deng, Zheng Liu, Guoan Luo, Hong Ma, Mingxing Duan.“Rapid quantitative determination and assessment of insulin in oil formulation by micellar electrokinetic capillary chromatography”, Journal of Pharmaceutical and Biomedical Analysis. 27 73 - 80 (2002).
• Liang Rong，Zhuang FengFeng, Meng Zheng, Zheng Changxue, Duan Mingxing.“A New Potent Route of DNA Vaccine Inoculation: DNA-Liposome Complexes on Bare Skin Induce Antigen-Special Antibody Responses”, Molecules 8, 120 126. (2003).
• Hong-Wei Wang, Yong Chen, Hsiuchin Yang, Xianchuan Chen, Ming-Xing Duan, Phang C. Tai and Sen-Fang Sui.“Ring Like Pore Structures of SecA: Implication for Bacterial Protein-Conducting Channels”. Proc.Natl.Acad.Sci.U.S.A. Vol.100 No.7 P4221-4226 (2003).
• Xi-Ming Qin，Ming-Xing Duan, Bin Deng, Xi-Cheng Liu, Qiang-Zhe Zhang, Zheng Liu, and Hong-Xuan He.“Isolation and Identification of a New Thymic Peptide from Calf Thymus”, Biochemistry(Moscow) 2004, 69(8): 921-925.
• HongXuan HE, BaoHua ZHAO, LiYan LIU，Kai ZHOU, XiMing QIN, QiangZhe ZHANG, Xi LI, ChangXue ZHENG, and MingXing DUAN.“The Humoral and Cellular Immune Responses in Mice Induced by DNA Vaccine Expressing the Sporozoite Surface Protein of Cryptosporidium parvum”, DNA AND CELL BIOLOGY Vol.23, No.5, P335-339 (2004).
• Zhang Qiang-Zhe, Qin Xi-Ming,Dong Hai-Li, Liang Rong, He Hong-Xuan,Li Xi, Jiang Bei-Yu, Liu Xiang-Jun, Duan Ming-Xing.“Efficient Protection of H5N1 Influenza Virus DNA Vaccine Delivering by Electroporation in Mammalian and Avian System”, Progress in Biochemistry and Biophysics Vol.32 No.8 p726-733 (2005).
• Hongxuan HE, Yi Tang, Ximing Qin, Wenbo XU, Yifei Wang , Xiangjun Liu, Xingyou Liu, Sheng Xiong, Jiuxiang Li, Meiying Zhang, Mingxing DUAN.“Construction of a eukaryotic expression plasmid encoding partial S gene fragments of the SARS- CoV and its potential utility as a DNA vaccine”. DNA and Cell Biology Aug 2005 Vol.24, No.8 516-520.
• Er-li MA, Hong MA, Zheng LIU, Chang-xue ZHENG, Ming-xing DUAN“ In vitro and in vivo evaluation of a novel oral insulin formulation” Acta Pharmacologica Sinica 2006 Oct,27(10):1382-1388
• GONG Qiu, LIU Zheng, ZHAO, Weigang, MA Hong, ZHANG Jing, MA Er-li, ZHENG, Chang-xue, DUAN Ming-xing“Studies on Administration and Mechanism of Insulin Oily Formulation”Chinese Pharmaceutical Journal 2007 Sep, Vol.42 No.17 P1320-1324
• Kai Zhou, Hongxuan He &8727;, YanyunWu, Mingxing Duan &8727;“RNA interference of avian influenza virus H5N1 by inhibiting viral mRNA with siRNA expression plasmids” Journal of Biotechnology 135（2008）140-144
• Wang Guan, Xu Min, Zhou Huafeng, Chen Bin, Yan Zemin, Duan Ming-xing. &8727;“Stady on Bile Acids From Bile Juice of Snake,Chicken and Pig by Reversed Phase High Performance Liquid Chromatography and their Antibacterial Effects”Modern Scientific Instruments, No.3 P50-55, Jun 2008.
• Chengmin Wang, Hongxuan He &8727;, Mingxing Duan“Development and evaluation of a recombinant CP23 antigen-based ELISA for serodiagnosis of Cryptosporidium parvum ” Experimental Parasitology 121（2009）157-162
• Jieli Deng,Zhonghan Sheng,Kai Zhou, Mingxing Duan &8727;, Chu-yi Yu &8727;, and Long Jiang &8727;“Construction of Effective Receptor for Recognition of Avion Influenza H5N1 Protein HA1 by Assembly of Monohead Glycolipids on Polydiacetylene” Bioconjugate Chemistry Vo.20 No.3 P533-537 (2009)
• Huafeng Zhou,Yang Yue,Guanlan Liu, Yan Li, Jing Zhang, Qiu Gong,Zemin yan,Mingxing Duan&8727;“Preparation and Characterization of a Lecithin Nanoemulsion as a Topical Delivery System” Nanoscale Research Letter (2010) 5:224–230.
• Yang Yue, Huafeng Zhou, Guanlan Liu, Yan Li, Zemin Yan, Mingxing Duan&8727;“The advantages of a novel CoQ10 delivery system in skin photo-protection”International Journal of Pharmaceutics 392(2010)57-63

联系方式

• 电话：+86-10-62773255
• 传真：+86-10-62773255
• E-mail: duanmx@mail.tsinghua.edu.cn