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黄仕勇

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黄仕勇(Shiyong Huang), Ph.D.

Investigator

Laboratory of Neural Circuits and Behavior 
Program in Neuroscience
Hussman Institute for Autism
801 W. Baltimore Street
Suite 301
Baltimore, MD 21201
443-860-2580 ext. 732
[email protected]





目录

教育经历编辑本段回目录

2015-present Adjunct Assistant Professor, Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 2014-present Investigator, Program in Neuroscience, Hussman Institute for Autism, Baltimore, MD 2013-2014 Associate Research Scientist, Johns Hopkins University, Baltimore, MD 2010- 2013 Assistant Research Scientist, Johns Hopkins University, Baltimore, MD 2006-2010 Postdoctoral Fellow, Johns Hopkins University, Baltimore, MD 2006 Ph.D. Neurobiology, Chinese Academy of Sciences, Shanghai, China 2001 B.S. Biochemistry, Wuhan University, Wuhan, China

研究方向编辑本段回目录

Employing a combination of cutting-edge approaches, including neural computational, electrophysiological, optogenetic, and imaging, we aim to measure and manipulate neural connectivity within genetically-defined circuits.  We expect to confirm causal links between these circuits and autism behavior.  Then we will use mouse models to develop potential treatments.

代表性论文:编辑本段回目录

Bridi M, Park SM, Huang S#. Developmental disruption of GABAAR-meditated inhibition in Cntnap2 KO mice. eNeuro 2017, 4(5): 0162-17.

 

Gao M*, Whitt JL*, Huang S*, Lee A, Mihalas S, Kirkwood A, Lee HK. Experience-dependent homeostasis of “noise” at inhibitory synapses preserves information coding in adult visual cortex. Phil. Trans. R. Soc. B. 2017, 372(1715). (*Equal contribution) (PMID: 28093550)

 

Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief dark exposure reduces tonic inhibition in visual cortex. J. Neurosci. 2015, 35: 15916-15920. (PMID: 26631472)

 

Huang S, Rozas C, Trevi?o M, Contreras J, Yang S, Song L, Yoshika T, Lee HK, Kirkwood A. Associative hebbian synaptic plasticity in primate visual cortex. J. Neurosci. 2014, 34: 7575-7579. (PMID: 24872561)

 

Huang S, Huganir RL, Kirkwood A. Adreneric gating of Hebbian spike-time dependent plasticity in cortical interneurons. J. Neurosci. 2013, 33: 13171–13178. (PMID: 23926270)

 

Gu Y*, Huang S*, Chang CM, Worley P, Kirkwood A, Quinlan E. Obligatory role for the immediate early gene NARP in critical period plasticity. Neuron 2013, 79: 335-346. (*Equal contribution) (PMID: 23889936)

 

Huang S*,Trevi?o M*, He K*, Ardiles A, De Pasquale R, Guo Y, Palacios A, Huganir RL, Kirkwood A. Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron 2012, 73: 497-510. (*Equal contribution) (PMID: 22325202)

 

Huang S*, Gu Y*, Quinlan E, Kirkwood A. A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure. J. Neurosci. 2010, 30: 16636-16642. (*Equal contribution) (PMID: 21148002)

 

Jiang B*, Huang S*, De Pasquale R, Millman D, Song L, Lee HK, Tsumoto T, and Kirkwood A. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron 2010, 66: 248-259. (*Equal contribution) (PMID: 20435001)

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