| 1. Hu R, Jin S, He X, Xu F and Hu J. (in press) Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System. Frontiers in Neuroanatomy (correspondence author) 2. Hu R, Zhang J, Luo M, Hu J. (in press) Response Patterns of GABAergic Neurons in the Anterior Piriform Cortex of Awake Mice. Cerebral Cortex (correspondence author) |
胡霁

胡霁,教育部长江学者特聘教授。上海科技大学研究员/博士生导师,副院长。目前担任中国神经科学会应激神经生物学分会副主任委员,中国神经科学会认知神经生物学分会副主任委员。获得国家青年千人,自然科学基金面上项目,自然科学基金优秀青年项目,自然科学基金重大研究计划,自然科学基金重大项目,科技部973计划支持。研究成果以通讯作者在Nature, Neuron,Current Biology,Science Advances等国际学术期刊发表系列论文。获得重庆市科技进步一等奖,中科院教学成果二等奖,上海市教学成果特等奖。2003年本科毕业于华中科技大学,同年进入中科院上海神经科学研究所。2005年随导师实验室转至北京生命科学研究所(NIBS)/中科院生物物理研究所,2008年获神经生物学博士学位。2009年开始在麻省理工学院Picower学习与记忆研究所(The Picower Institute for Learning and Memory at MIT)进行博士后研究工作。2013年1月回国,任职西安交通大学前沿科学技术研究院。2014年4月加入上海科技大学生命科学与技术学院任助理教授、研究员.
研究方向
行为的神经环路机制我们发展和应用光学成像、神经调控、遗传学标记与神经环路示踪等最新的方法精确地研究情感及其相关的精神类疾病的重要科学问题。实验室拥有国际领先且全面的光学成像仪器(双光子显微镜、梯度折射透镜、光纤光度测量)和技术手段,同时也将结合单细胞测序,质谱技术等前沿的分子生物学手段,深入研究以下重要的神经科学问题:1.应激/压力的神经机制;2.神经精神药理的环路机制;3.神经与精神疾病治疗的新策略。我们的研究将有助于重要的精神疾病比如抑郁症、焦虑症的治疗
Employment
Feb/2013 - Tengfei Group Leader
(腾飞小组主任) and jointly a deputy director of a lab (实验室副主任),
Center for Neuron and Disease, Frontier Institute of Science and
Technology (FIST), Xi’an Jiaotong University, China
May/2009-Feb/2013 Postdoctoral Associate, Picower Institute for Learning and Memory,
Massachusetts Institute of Technology
June/2008-May/2009 Postdoctoral Associate, National Institute of Biological Sciences,
Beijing
Education
Jan/2005-June/2008 Ph.D in Neuroscience
National Institute of Biological Sciences, Beijing
July/2003-Jan/2005 Ph.D student in Neuroscience
Institute of Neuroscience, Chinese Academy of Sciences
Sep/1999-June/2003 BS in Biotechnology
Huazhong University of Science and Technology, Wuhan, China
Representative Publications:
| 1. Yang Y, Wang H, Hu J*, Hu H* (2018). Lateral habenula in the pathophysiology of depression. Current Opinion in Neurobiology(*Co-corresponding author)(Advanced online) 2. Hu R, Zhang J, Luo M, Hu J*. (2017) Response Patterns of GABAergic Neurons in the Anterior Piriform Cortex of Awake Mice. Cerebral Cortex (*correspondence author) 3. Hu R, Jin S, He X, Xu F and Hu J*. (2016) Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System. Frontiers in Neuroanatomy (*correspondence author) 4. Gong R*, Ding C*, Hu J*, Lu Y, Liu F, Mann E, Xu F, Cohen MB and Luo M*. (2011) Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior. Science (*co-first author) 5. Luo, M., Sun, L. and Hu, J (2009). Neural detection of gases--carbon dioxide, oxygen--in vertebrates and invertebrates. Current Opinion in Neurobiology 6. Sun L, Wan H, Hu J, Han J, Matsunami H, and Luo M (2009) Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. PNAS 7. Hu J*, Zhong C*, Ding C, Chi Q, Walz A, Mombaerts P, Matsunami H, and Luo M (2007) Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem. Science (*co-first author) |
Specialized olfactory subsystem detect carbon dioxide
1. Hu J, Zhong C, Ding C, Chi Q, Walz A, Mombaerts P, Matsunami H, Luo M (2007)
Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse.
Science 317:953-957. (co-first author)

2. Sun L, Wang H, Hu J, Han J, Matsunamic H, Luo M (2009) Guanylyl cyclase-D in the
olfactory CO(2) neurons is activated by bicarbonate. PNAS 106:2041-2046.
Role of GC-C in midbrain dopamine neurons
1. Gong R, Ding C, Hu J, Lu Y, Liu F, Mann E, Xu F, Cohen MB, Luo M (2011) Role
for the Membrane Receptor Guanylyl Cyclase-C in Attention Deficiency and Hyperactive
Behavior. Science 333:1642-1646. (co-first author)


Optogenetics method to restore learning and memory in AD mouse model
1. Hu J, Penagos H, Deisseroth K, Wilson M, Tsai L. Optogenetical stimulation of
septohippocampal cholinergic pathway restores learning and memory in neurodegenerative
diseaseby hippocampal circuitry remodeling. (In preparation)

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