陈永龙

博士，中国科学院广州生物医药与健康研究院 研究员

邮件地址：chen_yonglong@gibh.ac.cn

简历： 

1999-2001，德国哥廷根大学博士后  

1995-1999，德国埃森大学博士  

1982-1989，西北师范大学学士，硕士 

2002-2007，德国哥廷根大学研究组长  

1989-1995，西北师范大学助教，讲师 

 研究领域： 胰腺发育的分子机制 胚胎干细胞的定向诱导分化 

 代表论著： 

Guo, X., Zhang, T., Hu, Z., Zhang, Y., Shi, Z., Wang, Q., Cui, Y., Wang, F., Zhao, H., Chen,Y. 2014. Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis. Development 141: 707-714. 

Zhang, T., Guo, X., Chen,Y. 2013. Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One 8, e65058. 

Zhao, H., Han, D., Dawid, I.B., Pieler, T., and Chen,Y. 2012. Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc. Natl. Acad. Sci. U S A. 109，8594-8599. 

Lei, Y., Guo, X., Liu, Y., Cao, Y., Deng, Y., Chen, X., Cheng, C.H., Dawid, I.B., Chen,Y., Zhao, H. 2012. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc. Natl. Acad. Sci. U S A. 109，17484-17489. 

Li, L., Wen, L., Gong, Y., Mei, G., Jinsong Liu, J., Chen,Y.  and Peng, T. 2012. Xenopus as a Model System for the Study of GOLPH2/GP73 Function: Xenopus golph2 Is Required for Pronephros Development. PLoS One 7, e38939. 

Han, D., Wen, L., and Chen,Y. 2012. Molecular Cloning of phd1 and Comparative Analysis of phd1, 2, and3 Expression in Xenopus laevis. The Scientific World Journal 2012:689287. 

Li, X., Han, D., Kam, R. K. T., Guo, X., Chen, M., Yang, Y., Zhao, H., and Chen,Y. 2010. Developmental expression of sideroflexin genes in Xenopus embryos.  Developmental Dynamics 239, 2742–2747. 

Wen, L., Yang, Y., Wang, Y., Xu, A., Wu, D., Chen,Y. 2010. Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. Developmental Dynamics 239, 2198-2207.