程和平

程和平

电子邮件: chengp(at)pku(dot)edu(dot)cn；

电话: +86-10-62765957；

实验室主页: http://www.imm.pku.edu.cn/news.php?id=250

 
研究方向:

钙信号与活性氧（ROS）信号：线粒体超氧炫 (Superoxide Flash)分子基础、调节机制及生理病理意义；钙信号与ROS信号调控心脏发育、再生；钙信号与ROS信号的计算-数学模型。

 
代表性科研论文:

1. Cheng HP*, Lederer WJ, Cannell MB, Calcium sparks: The elementary events underlying excitation-contractioncoupling in heart muscle. SCIENCE, 262, 740-744,1993.
2. Wang SQ, Song LS, Lakatta EG, Cheng HP*, Ca²⁺ signalling between single L-type Ca²⁺ channels and ryanodinereceptors in heart cells. NATURE, 410, 592-596, 2001.
3. Wang W, Fang HQ, Groom L, Cheng A, Zhang WR, Liu J, Wang XH, Li KT, Han PD, Zheng M, Yin JH, Wang W, MattsonM, Kao JPY, Lakatta EG, Sheu SS, Ouyang KF, Chen J, Dirksen RT, Cheng HP*, Superoxide flashes in single mitochondria. CELL, 134, 279-290, 2008.
4. Wei CL, Wang XH, Chen M, Ouyang KF, Song LS, Cheng HP*, Calcium flickers steer cell migration. NATURE, 457, 901-905, 2009.
5. Fang H, Chen M, Ding Y, Shang W, Xu J, Zhang X, Zhang W, Li K, Xiao Y, Gao F, Shang S, Li J, Tian X, Wang S, Zhou J,Weisleder N, Ma J, Ouyang K, Chen J, Wang X, Zheng M, Wang W, Zhang X, Cheng HP*, Imaging superoxide flash andmetabolism-coupled mitochondrial permeability transition in living animals. CELL RESEARCH, In press, 2011.