黄仕勇

2015-present Adjunct Assistant Professor, Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 2014-present Investigator, Program in Neuroscience, Hussman Institute for Autism, Baltimore, MD 2013-2014 Associate Research Scientist, Johns Hopkins University, Baltimore, MD 2010- 2013 Assistant Research Scientist, Johns Hopkins University, Baltimore, MD 2006-2010 Postdoctoral Fellow, Johns Hopkins University, Baltimore, MD 2006 Ph.D. Neurobiology, Chinese Academy of Sciences, Shanghai, China 2001 B.S. Biochemistry, Wuhan University, Wuhan, China

Employing a combination of cutting-edge approaches, including neural computational, electrophysiological, optogenetic, and imaging, we aim to measure and manipulate neural connectivity within genetically-defined circuits.  We expect to confirm causal links between these circuits and autism behavior.  Then we will use mouse models to develop potential treatments.

Bridi M, Park SM, Huang S. Developmental disruption of GABAAR-meditated inhibition in Cntnap2 KO mice. eNeuro 2017, 4(5): 0162-17. 

Gao M, Whitt JL, Huang S, Lee A, Mihalas S, Kirkwood A, Lee HK. Experience-dependent homeostasis of “noise” at inhibitory synapses preserves information coding in adult visual cortex. Phil. Trans. R. Soc. B. 2017, 372(1715). (Equal contribution) (PMID: 28093550)

 Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A. Brief dark exposure reduces tonic inhibition in visual cortex. J. Neurosci. 2015, 35: 15916-15920. (PMID: 26631472)

 Huang S, Rozas C, Trevi?o M, Contreras J, Yang S, Song L, Yoshika T, Lee HK, Kirkwood A. Associative hebbian synaptic plasticity in primate visual cortex. J. Neurosci. 2014, 34: 7575-7579. (PMID: 24872561)

 Huang S, Huganir RL, Kirkwood A. Adreneric gating of Hebbian spike-time dependent plasticity in cortical interneurons. J. Neurosci. 2013, 33: 13171–13178. (PMID: 23926270)

 Gu Y, Huang S, Chang CM, Worley P, Kirkwood A, Quinlan E. Obligatory role for the immediate early gene NARP in critical period plasticity. Neuron 2013, 79: 335-346. (Equal contribution) (PMID: 23889936)

 Huang S,Trevi?o M, He K, Ardiles A, De Pasquale R, Guo Y, Palacios A, Huganir RL, Kirkwood A. Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex. Neuron 2012, 73: 497-510. (Equal contribution) (PMID: 22325202)

 Huang S, Gu Y, Quinlan E, Kirkwood A. A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure. J. Neurosci. 2010, 30: 16636-16642. (Equal contribution) (PMID: 21148002)

 Jiang B, Huang S, De Pasquale R, Millman D, Song L, Lee HK, Tsumoto T, and Kirkwood A. The maturation of GABAergic transmission in visual cortex requires endocannabinoid-mediated LTD of inhibitory inputs during a critical period. Neuron 2010, 66: 248-259. (Equal contribution) (PMID: 20435001)